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Nausea affects approximately 24-44% of patients using GLP-1 receptor agonists like semaglutide and tirzepatide, though severity varies considerably
Polymorphisms of these genes or associated regulatory sequences, or copy number variations (CNV) may contribute to a reduction in UGT activity or indeed loss of function and, therefore, reduce paracetamol glucuronidation
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Whittle IR, Smith C, Navoo P, Collie D
Note: Always inform your healthcare provider about every supplement you take, including fiber, so they can monitor your progress and adjust your treatment plan if necessary
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