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The dose of BAY11-7082 was chosen based on our preliminary results of dose response, which showed that 10 M BAY11-7082 significantly increased the number of surviving SGNs after cisplatin damage in vitro (Supplementary Figure 2)
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The proposed mechanism most often cited involves copper transport, modulation of growth-factor signaling, and effects on the extracellular matrix
Could retatrutide be used for conditions beyond weight loss and diabetes
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