The prescribing clinician determines whether semaglutide, tirzepatide or an FDA-approved branded option is appropriate based on the patients health history
GLP-1 is released from the L cells in the gut in response to energy intake, and facilitates a multitude of physiological actions, including a delay in gastric emptying [27]
Medium (3 vials), the middle tier, is enough for constant use, but less than the High tier
approval is not guaranteed based on the above criteria
Additionally, semaglutide slows down gastric emptying, which helps to control appetite and promote weight loss
Clinical evidence from the STEP 4 trial found that participants who continued weekly semaglutide injections for up to 104 weeks (2 years) maintained significantly more weight loss compared to those who stopped treatment after initial success