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In vitro studies have shown that CD8 T cells have a predominant role in killing infected cells, whereas CD4 T cells collaborate with CD8 T cells and can also directly attack infected cells (122, 298, 299)
doi: 10.1056/NEJMoa1607141 18 HolmanRRBethelMAMentzRJThompsonVPLokhnyginaYBuseJBet al
Concurrently, an increase in adiponectin, an anti-inflammatory adipokine, was observed, suggesting a reprogramming of adipocyte secretion toward a protective phenotype
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