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Depletion of GSH could lead to inactivation of SAM synthetase, with further decrease in GSH concentrations

Furthermore, addition of NADPH together with lucigenin to suspensions of human [33], mouse [34] rat [32] wallaby [35] and stallion [36] spermatozoa demonstrated that this lucigenin-dependent redox activity is a ubiquitous feature of mammalian spermatozoa

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nicotinamide adenine dinucliotide phosphate hydrogen, NADPH

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