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Zebenholzer, Karin (Department of Neurology, Medical University of Vienna)
True allergic reactions involve immune hypersensitivity: hives, throat constriction, wheezing, chest tightness, difficulty breathing, or anaphylaxis
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it's about structural integrity
The most common side effects are mild and may include nausea, stomach discomfort, constipation, diarrhea, bloating, or fatigue
In endemic settings, immune responses and disease severity are influenced by multiple host factors, e.g., infection intensity, cumulative treatment history, co-infection status, genetics/genetic pre-disposition, and in utero transplacental and postnatal oral antigen sensitization resulting in phenotypically similar maternal and fetal responses (18, 26)
A unique finding is dysesthesia (tingling/altered sensation) in 20.9% at 12mg in TRIUMPH-4 and 12.5% in TRIUMPH-1
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