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Metabolism Regulation : It is involved in various metabolic processes, including the synthesis of proteins and DNA

305 At the therapeutic level, therapeutic vaccines targeting Arg 1 have been shown to activate antitumor immunity in a variety of syngeneic mouse tumor models such as lung cancer, melanoma, and colon cancer, and the combination of Arg 1 vaccine with anti-PD-1 antibody can increase T cell infiltration, inhibit myeloid cell function, and increase the ratio of tumor-infiltrating M1/M2 macrophages

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Promotes natural energy production

Specifically, we review targeted nanomedicine delivery systems engineered to home to bone tissue and reshape the TME landscape via strategies including TAM reprogramming, MDSC depletion, ECM clearance to relieve physical resistance, and activation of innate immune pathways