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The quieting is also where the headline results come from: in the STEP-1 trial, 1,961 adults on weekly semaglutide lost an average of 14.9% of body weight over 68 weeks, and in SURMOUNT-1, tirzepatide's top dose averaged 20.9% over 72 weeks - effects built in large part on appetite, and its chatter, turning down

Pharmacological properties of biogenically synthesized silver nanoparticles using endophyte Bacillus cereus extract of Berberis lyceum against oxidative stress and pathogenic multidrug-resistant bacteria

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3326-A TARGETING PKM2 IN NASH-HCC: CROSS TALK BETWEEN HEPATIC MACROPHAGE REGULATION AND TGF-BETA SIGNALING Kazufumi Ohshiro 1 , Krishanu Bhowmick 1 , Xiaochun Yang 2 , Dillon Voss 3 , Adrian R Krainer 3 and Lopa Mishra 1,3 , (1)The Institute for Bioelectronic Medicine, Feinstein Institutes for Medical Research, & Cold Spring Harbor Laboratory, Department of Medicine, Division of Gastroenterology and Hepatology, Northwell Health, Manhasset, New York, USA., (2)The Institute for Bioelectronic Medicine, Feinstein Institutes for Medical Research & Cold Spring Harbor Laboratory, Department of Medicine, Division of Gastroenterology and Hepatology, Northwell Health, NY, USA., (3)Cancer Center, Cold Spring Harbor Laboratory, NY, USA