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At higher doses, some concern exists about pro-inflammatory effects: LL-37 can activate NF-kB pathways, potentially worsening certain inflammatory conditions

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While no evidence directly links penta deca peptide arginate to cancer progression, the precautionary principle suggests avoiding pro-angiogenic compounds in individuals with known or suspected malignancies

Typically the busiest days at Hawaii airports are the days leading into the weekend and the days returning from the weekend