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This is consistent with emerging research
Some animal models have provided evidence suggesting that GLP1 is a physiologically relevant natriuretic factor that contributes to sodium balance, partly through the tonal modulation of the activity of sodium-hydrogen exchanger isoform 3 (NHE3) in the brush border of the proximal convoluted tubule 23 , 24
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Tirzepatide carries a boxed warning for thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
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