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Demand has caused scarcities & with scarcity came lucrative opportunities for compounding pharmacies that prescribe them to anyone wanting a quick weight fix
The trial data is published at NEJM, 2023
Some practitioners use microdosing approaches during the escalation to 15 mg, splitting the dose increase into smaller increments rather than jumping a full 2.5 mg at once
The answer to which option is best is fairly nuanced
doi: 10.1016/j.maturitas.2019.05.003 Summary Keywords GLP-1, estrogens, body weight, menstrual cycle, mental health Citation Vigil P, Melndez J, Petkovic G and Del Ro JP (2022) The importance of estradiol for body weight regulation in women
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