Another independent study uncovered a novel ANG signal peptide mutation, and careful analysis revealed an allelic association with the rs11701 nucleotide polymorphism (SNP) in familial ALS (FALS) (Conforti et al
Both effects respond to morning dosing and dose reduction to 250 mcg
doi:10.1016/0014-5793(88)80509-x Maquart FX, Bellon G, Chaqour B, et al
3 months and no relief later (The shot helped for about 2weeks) I got a recheck
But, estecially with Crohns, when foods don't digest and/or go through too fast, we don't get a chance to absorb the B12
Additionally, peptides should be kept in tightly sealed containers for example vials to protect them from moisture and air exposure, which can compromise their quality