Although THC possesses neuroprotective antioxidant properties through non-CB1R pathways [33], it also upregulates plasma inflammatory cytokines [34], increases vulnerability to ischemic stroke in young people [35], increases mitochondrial dysfunction [36, 37] and alters gene pathways associated with mitochondrial oxidative phosphorylation [38]
Nitric Oxide (NO) is one molecular mediator involved in both the inflammatory response [34] and oxidative damage [6, 35]
Therapeutic potential of resveratrol in diabetic nephropathy according to molecular signaling
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Presented for research literature review only Baek SM et al