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The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)
Ethics declarations RRM has received consulting fees from Nested Therapeutics (Cambridge, U.S.) and serves on the Scientific Advisory Board of CLOVES Syndrome Community
.,AzmanM,SabriAH,AnjaniQK,MustaffaMFHamidKAIntestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery.2022;15(8):975 51
Doe covered TPS designations for Haiti and Syria
Iron is essential for spermatogenesis and male reproductive function
Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis
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