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DATS also inhibited LPS-induced NF-B-dependent expression of COX-2, iNOS, tumor necrosis factor- (TNF-), and interleukin-1 (IL-1) (37)

Additionally, metformin has been shown to improve sputum culture conversion and lower the relapse rate of patients with TB-DM [122]

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Nutrition and hydration Collagen synthesis requires specific nutrients

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