It is not official but it is happening often In fact, I cannot see any scientific reason why GLP-1 based therapies could not be titrated similarly to insulin Advantages such as better tolerability or lower costs are there Perhaps time has come to discuss this with pharma (not only tirzepatide but also semaglutide and others) and test to make it official
Finally, a significant, direct correlation was observed between weight change and change in BMD at the pelvis
Another point to be considered is the 17 trials with unreported pancreatic cancer events, from which we only received replies of 4 authors
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The perception of obesity as a lack of willpower has long been a barrier to effective treatment
Whats more, the FDA has only approved Ozempic, not compounded semaglutide, for its safety and efficacy