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(2019), this paper reports the discovery of a GPX4-independent pathway for suppressing ferroptosis involving NADPH, FSP1 and ubiquinone
DOI: 10.1002/jcb.240550004
In one case study, a woman with bipolar disorder felt an uncomfortable euphoria while taking semaglutide that resolved when she stopped the medication, suggesting that certain GLP-1s could impact mood in at least some individuals
High doses can cause abdominal issues like cramping and bloating
Panc-1 cells (5 106/ml) transfected with shGSTM3 or shNC were injected into the groin of the mice with PBS (100 l suspension) subcutaneously
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