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Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that plays a significant role in regulating expression of antioxidant and cytoprotective enzymes in response to oxidative stress

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These bioactive compounds have anti-diabetic, anti-inflammatory, cardiotonic, antibacterial, anti-hemorrhoidal, antioxidant, anticancer, lipid-lowering, cytotoxic, and choleretic activities