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The protective effects of an injectable glucagon-like peptide-1 receptor agonist (GLP-1RA) on the heart and kidneys were recently revealed in several large-scale clinical trials, the LEADER [7], SUSTAIN-6 [8], AWARD-7 [9] and EXSCEL trials [10]
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Combination drugs Medications like Qsymia and Contrave are more likely to be on formularies since theyre older and less expensive than GLP-1s
The Kraus 2014 Nature paper established that NNMT is highly expressed in adipose tissue (especially in obesity) and that NNMT knockdown in adipose protects against diet-induced obesity in mice
Grey market scales linearly with milligrams
Because appetite suppressant medications can significantly reduce hunger, nutritional support also helps patients prioritize nutrient-dense foods that fuel the body properly
