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However, this combination regimen showed activity in patients with ovarian cancer who progressed on PARPi therapy in another phase II trial (EVOLVE) [221]
Male studies: Doses of 7-20 mg showed efficacy in men with ED, though with higher nausea rates
doi: 10.1152/ajpgi.1998.275.4.G862 249 IlcolYOYilmazZUlusIH
More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes
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Its purely acting on brain receptors
