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B1 (thiamine) deficiency, particularly common in alcohol users, damages peripheral nerves

20,21 Human studies have implicated numerous health benefits for EPA and DHA in inflammatory diseases

This applies to PPO, HMO, Medicare, and Medicaid

This leads to the release and subsequent cytoplasmic translocation of p53, which in turn activates a transcription-independent pro-apoptotic pathway, facilitating the selective clearance of senescent cells (Kong et al., 2025