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Increased levels of 8-OHdG and isoprostanoids have been observed in the urine of subjects affected by the disease compared to the control group (Miller et al., 2014)
Notably, adaptive therapy prolonged the time to progression to at least 27 months compared with approximately 16.5 months under standard dosing, while reducing cumulative drug exposure by nearly half
Priscilla M
Additionally, Toxins and ROS can damage mitochondrial DNA and membranes, leading to impaired ATP production
J.RadfordR
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