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Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations

Important items include a timeline of symptoms, list of medications and supplements, relevant medical history (diabetes, smoking, prior surgeries), photographs of any color changes or skin lesions, and a note of triggers that worsen or improve the sensation

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Although no direct ligand has been identified for HER2/neu, it can be activated through overexpression or transactivation by ligands of other EGF family receptors (37, 60, 61) In addition, the phosphatase protein tyrosine phosphatase 1B (PTP1B) regulates tyrosine kinase signalling by dephosphorylating key kinases involved in breast tumourigenesis, including HER1/EGFR, proto-oncogene tyrosine-protein kinase (Src), janus kinase (JAK), and signal transducer and activator of transcription (STAT)

2020;26:e923232