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Ensayos clave SUSTAIN-6 (DM2, MACE), PIONEER-6 (oral, DM2), SOUL (oral, DM2+ECV/ERC), STEP 1-5 (obesidad), SELECT (obesidad+ECV, sin DM), STEP-HFpEF (ICFEp), FLOW (ERC+DM2)
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A study published in the Journal of Clinical, Cosmetic, and Investigational Dermatology found that oral glutathione supplementation improved skin elasticity and reduced wrinkles in participants after several weeks of consistent use
and (3) a group supplemented with 4 mM L-proline
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However, their exact contribution to myocardial dysfunction remains unclear
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