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These improvements were linked to changes in brain tissue, where certain genes involved in blood vessel growth and brain protection became more active, which may explain how healing happened

doi: 10.1159/000064415 6

However, these emerging markers are still in the basic research stage, lacking large samples to validate their clinical sensitivity, specificity and predictive value, and the refinement of telomere length shortening measurement to the extent that it is substantially associated with the developmental potential of the embryo has yet to be thoroughly investigated

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