VAT is the deep fat compartment that surrounds abdominal organs, elevates cardiovascular and metabolic risk markers, and tends to be resistant to diet and exercise interventions that reduce subcutaneous fat
Fatigue may indicate healing process requiring rest (growth hormone naturally increases during sleep, healing metabolically demanding)
Both medications regulate appetite and promote fullness by activating the GLP-1 hormone, but tirzepatide takes things a step higher by also activating the GIP hormone for better results
Enhanced collagen synthesis aids in repairing and strengthening these tissues
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When IGF-1 binds to its receptor on muscle cells, it activates signaling pathways that promote protein synthesis and inhibit protein breakdown