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Finally, the peripheral inflammatory cytokines can not only cross the BBB but also bind to receptors on endothelial cells to activate the production of prostaglandins (PGs), which promotes neuroinflammation (Schiepers et al., 2005
their reduction directly undermines the structural and functional integrity of the BTB ( Figure 3 )
It works by reducing the appearance of dark spots and evening out skin tone
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De Simone C, Famularo G, Tzantzoglou S, Trinchieri V, Moretti S, Sorice F
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