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If your cells are responding poorly to insulin, a GLP-1 addresses this indirectly through weight loss and blood sugar regulation

Inhibition of SGLT2 reduces sodium reabsorption in the proximal tubule and enhances Na + delivery to the macula densa, promoting finally the TGF activation with consequent afferent arteriole vasoconstriction and reduction of the single-nephron-glomerular-filtration-rate ( Figure 1 )

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Those with stable, quiescent disease may be reasonable candidates, provided they understand the importance of monitoring for symptom changes and maintaining close communication with both their gastroenterologist and prescribing physician

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The study included 56 patients (49 women), making it relatively small