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Notably, mutations in TP53 not only change its conformation but also cause p53 aggregation, and p53 aggregation in cells is more consequential than conformational changes

FLS, fibroblast-like synoviocytes

Specifically, in Parkinsons disease (PD) a drop in GSH is often one of the first signs of the development of disease due to the fact that an absence of the antioxidant causes nerve damage, cell death, and oxidative stress

Aggressive agitation breaks peptide bonds

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