The peptide does not suddenly become inert at day 29, but degradation is a gradual process, and the 28-day guideline provides a reasonable margin of safety
The actual concentration curves in living humans may differ
If side effects do occur, they are generally mild and may include: Pain, discomfort, swelling, or redness at the injection site Diarrhea Headache Bloating Nausea Numbness or tingling Serious side effects are rare and may include: Confusion Dizziness or fainting Muscle pain, cramps, or weakness Extreme thirst Facial flushing Frequent urination Palpitations Fatigue Difficulty breathing Coughing or noisy breathing (wheezing) Extreme pain, swelling, warmth or tenderness in one leg Difficulty swallowing Rash Itching over the body If you experience serious side effects, contact your doctor right away
This research provides additional evidence to suggest that discontinuing GLP-1 agonists at least 14 days before total joint replacement surgery is optimal to reduce the risk of delayed emergence from anesthesia, aspiration events, aspiration pneumonitis and conversion to intubation, said John R
Discussing Fertility Concerns with Your Healthcare Provider If you are taking or considering GLP-1 medication and have concerns about fertility, open communication with your healthcare provider is essential
PMID: 3 LiJXCumminsCL