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Studies show that it has a similar mechanism of action as AOD9604

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A 1987 study on mice determined oral glutathione to be nontoxic,27 and a 2017 toxicity study (also on mice) found that glutathione's LD (the amount of a substance needed to kill 50% of all test animals in one dose) was 5g/kg.6 An equivalent toxic dose for an 80kg human would be 32.5g, which is more than 32 times the highest amounts used in clinical studies

Cognitive Impairment Models: Dihexa has been tested in scopolamine-induced amnesia models and aged rat models, where it demonstrated restoration of cognitive performance on spatial memory tasks

Collectively, these results validate TMT-TAILs as an effective strategy for off-target substrate nomination and suggest that X(PC) induces a multipathway cell death response by cleaving endogenous caspase targets across both apoptotic and inflammatory pathways