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Table of Contents Why POTS Can Develop After Bariatric Surgery POTS after bariatric surgery is thought to result from reduced blood volume, autonomic deconditioning, and nutritional deficiencies particularly thiamine, B12, iron, and copper though no confirmed causal relationship has been established by NICE or the MHRA

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Reported protocols commonly describe a loading phase of roughly 250 mcg per subcutaneous dose daily for about 12 weeks, sometimes titrated toward 500 mcg if tolerated, followed by a maintenance phase of about 500 mcg one to three times per week

Avoid during pregnancy or breastfeeding unless advised by a doctor

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