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It works upstream in the endocrine axis
Specifically, nerve damage caused by vitamin B12 most often affects the extremities (hands and feet)
Hormonal replacement in hypopituitarism in adults: an Endocrine Society clinical practice guideline
Depression, memory loss, and behavioral changes B12 Deficiency Treatments You may require shots of B12 at first
NAD+ also supports DNA repair, cellular stress responses, and the regulation of inflammation, as well as the function of key longevity proteins called sirtuins
& Abeles, R
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