Notably, various exendin-4-based GLP-1RAs (Exenatide: 39 aa and Lixisenatide: 44 aa), and GLP-1-based GLP-1RAs (Dulaglutide: 31 aa, Liraglutide: 31 aa, Semaglutide: 31 aa, Tirzepatide: 39 aa, and Albiglutide: 60 aa) have been developed and approved by the FDA between 2005 and 2022 for the management of T2DM (Liu, 2024)
NICE guidance (NG28) recommends GLP-1 receptor agonists for adults with type 2 diabetes according to specific criteria, including BMI thresholds and previous therapy response
Promote FAT METABOLISM - for a more long-lasting source of energy
Constipation Slowed digestion can lead to bloating and constipation
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Those who qualify for Ozempic specifically will have a Body Mass Index, or BMI, higher than 30 and are pre-diabetic or diabetic