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Epigenetic reprogramming in cancer drug resistance and combating strategies Phenotypic and epigenetic reprogramming Epigenetic regulation, which governs heritable yet reversible changes in gene expression without altering the underlying DNA sequence, has emerged as a pivotal driver of therapeutic resistance across cancer types (Fig

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Glutathione works by inhibiting tyrosinase, an enzyme involved in melanin production, leading to a gradual brightening effect

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