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A titration tolerability study (PMC) found that patients who followed the standard titration protocol had meaningfully better tolerability outcomes than those who escalated faster
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Once completed, eligible patients are scheduled for a virtual consultation and may begin treatment quickly
In mammals, including humans, circulating IGF1 levels increase at the onset of puberty, and the administration of IGF1 advances the process of puberty [15, 16]
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For instance, recent studies in mouse models have revealed that astrocytes maintain an intracellular lactate reservoir that can be rapidly mobilized in response to neuronal cues such as elevated extracellular K + or membrane depolarization
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