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No adverse effects upon fertility were observed in male and female rats at oral doses up to 40 mg/kg pioglitazone daily prior to and throughout mating and gestation (approximately nine times the MRHD based on mg/m2)
Baseline labs typically include IGF-1 (the main downstream marker of GH activity), a Comprehensive Metabolic Panel, lipids, and HbA1c
Barden CJ, Wu F, Fernandez-Murray JP, Lu E, Sun S, Taylor MM, Rushton AL, Williams J, Tavasoli M, Meek A, Reddy AS, Doyle LM, Sagamanova I, Sivamuthuraman K, Boudreau RTM, Byers DM, Weaver DF, McMaster CR
Shunt narrowing or blockage can occur within the first year after the TIPS procedure
Target 0.7-0.8g per pound of body weight daily, distributed across 4-5 smaller meals
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