who discovered glp-1 Xenopus GLP-1-inspired discovery of novel receptor agonists as long-acting hypoglycemic and insulinotropic agents with significant therapeutic potential JCI - Discovery, characterization, and

When molecules go through oxidation, they produce toxins known as free radicals

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3.1 Riboflavin transporter deficiency Riboflavin transporter deficiency (RTD)historically termed BrownVialettoVan Laere or Fazio-Londe syndromeis a rare, early-onset motor neuron disease that couples the biochemistry of riboflavin with overt neurodegeneration ( SLC52A2 or SLC52A3 abrogate membrane uptake of riboflavin, precipitating secondary FMN/FAD depletion in metabolically demanding neurons and glia ( Mechanistic work in patient fibroblasts and iPSC-derived motor neurons confirms that transporter mutations collapse intracellular FMN/FAD pools, impair respiratory-chain flux and trigger neurite loss

All cited studies are conducted in cellular or rodent systems consistent with RUO classification

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