Suitability is always assessed in consultation
further notes that NICE CKS guidance states that treatment of B12 deficiency in people with neurologic involvement should include injections on alternate days until there is no further improvement
The main downside is that injections require more care
A 2026 UK review of the Molecular Psychiatry meta-analysis of 31 trials, the 2:1 caffeine + L-theanine stack, the alpha-wave and GABA mechanism, the sleep and stress data, the honest EFSA caveat and its excellent safety versus Dihexas unproven HGF/c-Met synaptogenesis and the c-Met concern
Unless otherwise prescribed by the doctor, the usual dose is: At the beginning of the treatment, 1 ml (1 ampoule) is administered once or twice a week in the first two weeks after the diagnosis, corresponding to 1000 - 2000 g cyanocobalamin per week
GHK-Cu may influence (which I did not expect): Transcriptomics: Over 4,000 human genes modulated in studiesmany tied to wound healing, antioxidant defense, and anti-fibrosis