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In this work we have highlighted the importance of the Rab6 HVD sequence for Ric1-Rgp1 activation in vitro and Rab6 localization in vivo
The findings open the door to a possible dual-purpose role for these drugs in treating both systemic inflammation and cardiovascular comorbidity in RA
The compound does not appear to be mutagenic or carcinogenic based on available preclinical data, though long-term safety studies in this area remain limited
2000;143(5):R79
Its main biological role is to act as a copper chaperoneit transports and delivers copper to cells that need it
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