10.1001/archinte.166.9.1003 146 RazayG.VreugdenhilA.WilcockG
In the SURMOUNT-1 trial, tirzepatide showed significant weight loss results in adults without diabetes over 72 weeks (15-21% body weight reduction, depending on dose), while orlistat typically produces more modest results (approximately 3-5% additional weight loss beyond placebo at 1 year)
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while marking its entry into Germany, France, Ireland and Spain
Notez que chez la majorit des participants, la perte de poids obtenue est largement suprieure 5 % du poids initial (le minimum associ une amlioration de la sant) et excde mme 20 % chez plusieurs dentre eux, en particulier chez les participants qui ont reu le tirzepatide
Precision psychiatry: a neural circuit taxonomy for depression and anxiety