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has guided thousands of patients to learn how these shots work, how long their effects can last, and what factors might affect their duration

Alternative GLP-1 receptor agonists If semaglutide causes significant side effects or concerns about b12 status arise, other GLP-1 medications offer alternatives

Anyone with digestive conditions affecting absorptionincluding Crohns disease, celiac disease, or history of procedures affecting stomach or intestinesneeds the digestive bypass injections provide

[1] [3] This route is particularly valuable for individuals with malabsorption conditions or severe deficiency states

Older adults with food-cobalamin malabsorption , where the stomach acid needed to release B12 from food has dropped with age

PMID 25327251