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Kwok, T
The relevant research question is whether intracellular NNMT inhibition produces pathway-specific effects under defined laboratory conditions, or whether broader changes in nicotinamide metabolism, NAD + availability, SAM-dependent methylation balance, and related biochemical pathways may influence additional cellular systems
The most commonly reported cardiovascular effect is the hot flash or flushing sensation mentioned earlier
This has driven studies into its effects on muscle strain, tendon integrity, ligament resilience, and joint health
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