Given the established relationship between TMAO production and intestinal microbiota, we were interested in the effects of antibiotics in our organic acidemia cohort
PLOS ONE 8, e69010
In the pursuit of drug development, there are many constraints that must be satisfied as the pharmacokinetics, pharmacodynamics, safety and tolerable limits, delivering modalities and translatability from preclinical to clinical models (135)
Gogineni P, Melson E, Papamargaritis D, Davies M
Injection site reactions are not applicable to this orally disintegrating tablet formulation, representing an advantage over injectable GLP-1 receptor agonists
These medications, known as GLP-1 receptor agonists (GLP-1-RAs), offer promising therapeutic options for type 2 diabetes and obesity-related conditions, including cardiovascular disease (CVD) and non-alcoholic fatty liver disease (NAFLD) (6)