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At the same time, the findings for clinical studies were more mixed, and long-term trials showed the possibility of a lower dementia risk with these drugs, but shorter trials did not show consistent cognitive improvements
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Furthermore, certain spontaneous reports lacked validation from healthcare professionals, and there was an absence of data regarding the patients physical conditions, familial history, and individual histories of alcohol and tobacco use, all of which could potentially affect cancer development
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However, translating the promising preclinical results of (-)-Vestitol and Salviolone into clinical success for AD treatment faces several significant hurdles