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Particles manually selected from 15 micrographs were used to train a model in the particle picking tool Topaz v0.2.5a 61

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systematically compared the transduction distribution of AAV1, 2, 5 and 8 serotypes in the knee joints of mice and found that different AAV serotypes showed different tissue tropisms in tissues such as synovium, cartilage and subsynovial bone (181)