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Coffee enemas have been used to assist in detoxification and have been used in some alternative cancer treatments because of their impact on liver detoxification
Evidence for depression is mixed
Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinsons disease
Biochim Biophys Acta 1780(11): 121735
Andrologia 2019;51:e13396 Salonia A, Bettocchi C, Carvalho J, Corona G, Jones TH, Kadiolu A, et al
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That is why the date rule exists alongside the visual check rather than instead of it
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