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Sulfation is also key for metabolizing xenobiotics, which are environmental toxins that can cause serious damage in the body

Available from: Ray-Coquard I, Leary A, Pignata S, Cropet C, Gonzlez-Martin A, Marth C, et al

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Several studies have explored its therapeutic application in experimental models of sepsis (Table 2)

T., Atisso, C

In accordance with the glutathione activator hypothesis, only positively charged amino acids replace Lys105 in enzymatically active glutaredoxins, whereas in inactive isoforms and other members of the thioredoxin superfamily the activator candidate is often separated from the catalytic cysteine residue in the primary sequence or is replaced by uncharged residues 3,11,12 (Fig