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10.1007/s10096-019-03674-0 197 MemarianiH.MemarianiM.Shahidi-DadrasM.NasiriS.AkhavanM
Furthermore, studies undertaken in vitro using isolated mouse hepatocytes have revealed that AMAP has a markedly reduced propensity to cause cytotoxicity when compared with acetaminophen, even though AMAP treatment results in higher levels of covalent binding to proteins (Holme et al
Results vary depending on the study design, model, and conditions used
A very large fraction of published binding constants for melanocortin ligands, including those for cyclic analogues, peptidomimetics and candidate subtype-selective compounds, are reported as inhibition of I-NDP-alpha-MSH binding to membranes from cell lines stably expressing a single human receptor subtype
doi: 10.2215/CJN.0000000000000533 22 BugnicourtJ
Bhattamisra SK, Shak AT, Xi LW, Safian NH, Choudhury H, Lim WM, Shahzad N, Alhakamy NA, Anwer MK, Radhakrishnan AK, Md S
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