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In the end, these routes converge to trigger the activation of execution caspases, particularly caspase-3, resulting in the fragmentation of poly-ADP-ribose-polymerase (PARP) (52)

This is an unlikely scenario as the developed worlds dietary intake of sulfur amino acids is generally adequate

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Additionally, c-Myc can transcriptionally upregulate the expression of the cystine/glutamate antiporter SLC7A11, facilitating the export of intracellular glutamate from the cell while promoting the uptake of extracellular cystine

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